Creamy Cajun Chicken Pasta with Parmesan, Garlic, and Mozzarella

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This creamy Cajun chicken pasta is a flavor-loaded dinner that brings comfort and spice together on one plate. Juicy, spice-rubbed chicken is seared to perfection and sliced over a bed of rich, garlicky penne pasta coated in a velvety sauce made from a trio of cheeses: sharp Parmesan, melty mozzarella, and creamy heavy cream.

Every bite delivers that Cajun warmth balanced with garlicky depth and cheesy indulgence. Whether you’re planning a weeknight meal or need a dish that feels a little more special, this pasta does it all. It’s bold, savory, and has just the right kick to keep you coming back for seconds.

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Preparation Phase & Tools to Use

Creating this Creamy Cajun Chicken Pasta doesn’t require fancy equipment, but having the right tools ensures a smooth and delicious result:

• Cast iron skillet or heavy-bottomed pan: Crucial for getting that golden-brown sear on the chicken while locking in moisture and flavor.
• Large pot: Needed for boiling pasta efficiently without clumping.
• Strainer: Helps quickly drain the pasta to stop the cooking process while preserving a touch of pasta water if needed.
• Tongs or spatula: Allows for easy turning of chicken without tearing.
• Microplane or grater: For freshly grated Parmesan which melts better and adds more flavor than pre-packaged cheese.
• Whisk: Essential for creating a smooth, lump-free sauce.

With these tools prepped and ready, you’ll make this creamy, spicy comfort dish effortlessly.

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Ingredients for the Creamy Cajun Chicken Pasta with Parmesan, Garlic, and Mozzarella

Each ingredient in this pasta dish plays a flavorful and functional role:

• Boneless, skinless chicken breasts: These are perfect for soaking up Cajun spices and cook quickly while staying juicy.
• Cajun seasoning: Brings heat, smokiness, and the signature flavor profile of this dish.
• Olive oil and butter: Used to sear the chicken and build a rich base for the sauce.
• Garlic cloves: Freshly minced garlic adds robust depth to the cream sauce.
• Heavy cream: Forms the creamy backbone of the pasta sauce, creating a smooth, rich texture.
• Parmesan cheese: Adds a sharp, salty edge and helps thicken the sauce.
• Mozzarella cheese: Melts beautifully into the sauce, giving it that stretchy, creamy finish.
• Penne pasta: Its tube shape holds sauce well, making every bite flavorful.
• Fresh parsley: A pop of color and herby brightness to balance the rich flavors.

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How To Make the Creamy Cajun Chicken Pasta with Parmesan, Garlic, and Mozzarella

Step 1: Season and Sear the Chicken

Rub Cajun seasoning generously onto both sides of the chicken breasts. In a hot skillet with a mix of olive oil and butter, sear each side for 5-6 minutes until cooked through and golden. Let rest, then slice.

Step 2: Cook the Pasta

Boil a pot of salted water and cook penne until al dente. Drain and set aside, reserving 1/4 cup of pasta water if needed to loosen the sauce.

Step 3: Build the Cream Sauce

In the same skillet, melt a bit more butter and sauté garlic until fragrant. Pour in the heavy cream and bring to a simmer. Stir in the Parmesan and mozzarella until melted and smooth.

Step 4: Combine and Finish

Toss in the cooked penne and mix until coated. Add sliced chicken on top, sprinkle with parsley, and serve immediately.

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How to Serve and Store Creamy Cajun Chicken Pasta with Parmesan, Garlic, and Mozzarella

To serve this dish at its best, plate the creamy pasta first, then top with slices of Cajun-spiced chicken. Garnish with freshly chopped parsley and a pinch of red pepper flakes if you like extra heat. This pasta pairs beautifully with garlic bread or a crisp side salad to balance the richness.

For storing leftovers, let the pasta cool completely, then transfer it to an airtight container. It will keep well in the refrigerator for up to 4 days. To reheat, add a splash of cream or milk and warm gently on the stovetop or in the microwave until creamy again.

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Frequently Asked Questions

How spicy is this dish?

It has a moderate kick from the Cajun seasoning, but you can adjust the spice level by using less or adding more, depending on your heat tolerance.

Can I use a different pasta?

Absolutely. Fettuccine, rotini, or rigatoni all work well and hold onto the creamy sauce nicely.

What if I don’t have Cajun seasoning?

You can make your own blend using paprika, garlic powder, onion powder, thyme, oregano, cayenne, and black pepper.

Can I use chicken thighs instead of breasts?

Yes! Thighs are juicier and more forgiving, though they may require a few extra minutes to cook through.

Is this freezer-friendly?

It can be frozen, but the texture of the cream sauce may change. For best results, enjoy it fresh or store it short-term in the fridge.

What can I substitute for heavy cream?

You can try half-and-half or a mix of milk and cream cheese, though the sauce may be slightly less rich.

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Want More Pasta Ideas with a Kick?

If you enjoyed this Creamy Cajun Chicken Pasta, you might love exploring these bold and flavorful pasta recipes too:

• Sweet Spicy Garlic Honey BBQ Chicken Pasta with the perfect tangy-sweet balance.
• One-Pot Chicken Parmesan Mac & Cheese for creamy comfort in one pan.
• Spicy Cajun Garlic Butter Sausage Pasta that delivers smokiness and spice.
• Creamy Jamaican Shrimp Rasta Pasta for a Caribbean twist on creamy pasta.
• Beef and Rotini in Garlic Parmesan Sauce if you’re craving a beefy garlic hit.

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📌 Save this recipe to your Pinterest dinner board so it’s ready when those creamy pasta cravings hit: Life With Olivia on Pinterest

Have you tried this Cajun Chicken Pasta? I’d love to hear how it turned out! Did you add more cheese? Swap the chicken for shrimp? Drop your twist or question in the comments—sharing your kitchen adventures is what makes this community flavorful.

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