Looking for the ultimate comfort food that brings together two classics? Meet Mac and Cheese Meatloaf—a cheesy, savory mashup of creamy macaroni and hearty ground beef meatloaf that delivers flavor in every bite. This is not your average meatloaf; it’s a family-style casserole that layers gooey mac and cheese on top of a juicy meatloaf base, then bakes to golden perfection.
Whether you’re prepping for a cozy weeknight dinner or want a potluck showstopper, this dish promises to satisfy. It’s indulgent, nostalgic, and surprisingly easy to make. Plus, it reheats like a dream—making leftovers a bonus, not a burden.
Preparation Phase & Tools to Use
Before diving into the delicious details, let’s make sure you’re set up for success with the right tools:
- Mixing Bowls: Use large mixing bowls to combine the meatloaf ingredients thoroughly without spillage.
- Box Grater or Food Processor: Shredding cheese fresh makes all the difference in texture and flavor.
- 9×13-Inch Baking Dish: This dish allows the meatloaf to cook evenly and gives enough surface area for the mac and cheese topping to spread beautifully.
- Skillet or Saucepan: Needed to prepare the cheese sauce for the mac and cheese base.
- Whisk: Essential for creating a smooth cheese sauce without lumps.
- Oven Thermometer (optional): Helps ensure your oven’s true temperature for accurate baking.
Setting up your space with these tools means less stress and better results once everything comes together in the oven.

Ingredients for the Mac and Cheese Meatloaf
Each component in this dish plays a key role in its comforting flavor and satisfying texture. Here’s what you’ll need:
- Ground Beef: Acts as the hearty foundation of the dish. Use 80/20 for a balance of flavor and moisture.
- Breadcrumbs: Binds the meatloaf mixture while absorbing excess moisture.
- Eggs: Essential for structure and holding the meat mixture together.
- Onion (finely diced): Adds moisture and a mild sweetness to the meatloaf.
- Garlic Powder & Onion Powder: Provide an underlying savory punch.
- Salt and Pepper: Basic seasoning to enhance all other flavors.
- Elbow Macaroni: Classic pasta shape that holds cheese sauce perfectly.
- Butter and Flour: These form the roux, the base of a rich and creamy cheese sauce.
- Milk: Brings the sauce to a smooth, pourable consistency.
- Cheddar Cheese (shredded): Sharp and melty—the star of the cheese sauce.
- Paprika or Smoked Paprika (optional): Adds color and a touch of warmth to the top layer.
How To Make the Mac and Cheese Meatloaf
Step 1: Create the Meatloaf Base
Preheat your oven to 375°F (190°C). In a large mixing bowl, combine ground beef, breadcrumbs, eggs, diced onions, garlic powder, onion powder, salt, and pepper. Mix until just combined—avoid overmixing for a tender texture.
Step 2: Shape and Bake the Meatloaf
Press the meat mixture into a greased 9×13-inch baking dish, shaping it into a flat, even layer. Bake uncovered for 25–30 minutes until the meat is mostly cooked through but not fully browned.
Step 3: Cook the Macaroni
While the meatloaf bakes, bring a large pot of salted water to a boil and cook the elbow macaroni according to package instructions. Drain and set aside.
Step 4: Make the Cheese Sauce
In a saucepan over medium heat, melt butter and whisk in flour to create a roux. Slowly add milk while whisking continuously. Once thickened, stir in shredded cheddar cheese until melted and smooth.
Step 5: Assemble the Layers
Spread the cooked macaroni evenly over the partially baked meatloaf. Pour the cheese sauce generously over the top, smoothing it with a spatula.
Step 6: Final Bake
Return the dish to the oven and bake for an additional 15–20 minutes, or until the top is bubbly and golden. Let rest for 5 minutes before slicing.
How to Serve and Store Mac and Cheese Meatloaf
Serve this dish straight from the oven while it’s warm, melty, and comforting. It makes a complete meal on its own, but it also pairs wonderfully with a crisp green salad or simple steamed veggies to balance the richness. For added flair, sprinkle chopped parsley or a pinch of smoked paprika just before serving.
When it comes to storing, this recipe is a dream. Let the dish cool to room temperature, then cover tightly or transfer to an airtight container. It keeps well in the fridge for up to 4 days. Reheat individual portions in the microwave or rewarm larger amounts in the oven at 325°F until hot and bubbly.
Freezing? Absolutely! You can freeze baked slices wrapped in foil or freezer-safe containers for up to 2 months. Thaw in the fridge overnight and reheat as needed.
Frequently Asked Questions
How can I keep my meatloaf from drying out?
Use 80/20 ground beef and avoid overbaking. Adding finely diced onions helps lock in moisture too.
Can I use other cheeses besides cheddar?
Absolutely! Monterey Jack, mozzarella, or a blend can create different flavor profiles. Just be sure they melt well.
What pasta shapes work best?
Elbow macaroni is traditional, but small shells or cavatappi hold cheese sauce just as well.
Can I make this dish ahead of time?
Yes! Assemble the entire dish, cover tightly, and refrigerate up to 24 hours before baking. Add 5–10 minutes to your bake time if starting from cold.
Is this recipe kid-friendly?
Definitely! Kids love the cheesy topping, and you can sneak in finely shredded veggies in the meatloaf for a hidden nutrition boost.
How do I know the meatloaf is cooked through?
Use a meat thermometer. The center should reach 160°F (71°C) to ensure it’s safely cooked.
Want More Comfort Food Ideas?
If Mac and Cheese Meatloaf won your heart, you’ll love these other satisfying, cozy meals:
- Longhorn Parmesan Chicken for a crispy, cheesy twist on chicken night.
- Cheesy Spinach Stuffed Shells if you crave something creamy and vegetarian.
- Deep Dish Pizza Cupcakes for a fun, handheld dinner option.
- Chicken Cordon Bleu Casserole when you want something extra indulgent.
- Philly Cheesesteak Sloppy Joes for all the flavor of a sandwich in a quick skillet meal.
For even more cheesy, hearty comfort food dishes, visit my Pinterest where I share daily recipes you’ll love: Life With Olivia on Pinterest
Save This Recipe for Later
📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.
And let me know in the comments how yours turned out. Did you go classic with cheddar or mix in something spicy like pepper jack? Maybe you added bacon bits on top?
I love hearing how others make these recipes their own. Questions are welcome too—let’s help each other cook smarter and eat happier.

Mac and Cheese Meatloaf
- Total Time: 65 minutes
- Yield: 6 servings
Description
This Mac and Cheese Meatloaf combines two classic comfort foods into one hearty dish. A juicy, savory meatloaf forms the base, topped with rich, creamy mac and cheese that bakes to golden perfection. Perfect for family dinners or potluck gatherings!
Ingredients
1 ½ pounds ground beef
½ cup breadcrumbs
2 large eggs
½ cup finely diced onion
1 teaspoon garlic powder
1 teaspoon onion powder
1 teaspoon salt
½ teaspoon black pepper
8 ounces elbow macaroni
3 tablespoons butter
3 tablespoons all-purpose flour
2 cups milk
2 cups shredded cheddar cheese
½ teaspoon paprika or smoked paprika (optional)
Instructions
1. Preheat oven to 375°F (190°C).
2. In a large bowl, mix ground beef, breadcrumbs, eggs, onion, garlic powder, onion powder, salt, and pepper until just combined.
3. Press meat mixture into a greased 9×13-inch baking dish. Flatten evenly.
4. Bake uncovered for 25–30 minutes until partially cooked.
5. While baking, boil macaroni in salted water according to package instructions. Drain and set aside.
6. In a saucepan, melt butter and whisk in flour to form a roux.
7. Gradually add milk, whisking until thickened.
8. Stir in shredded cheddar cheese until fully melted and smooth.
9. Layer cooked macaroni on top of baked meatloaf. Pour cheese sauce over evenly.
10. Return to oven and bake another 15–20 minutes until bubbly and golden on top.
11. Let rest for 5 minutes before slicing and serving.
Notes
Don’t overmix the meatloaf ingredients—gentle mixing ensures tenderness.
Use freshly shredded cheese for the smoothest, richest cheese sauce.
Let the dish rest before slicing to help it hold its shape.
- Prep Time: 20 minutes
- Cook Time: 45 minutes
- Category: Dinner
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 slice
- Calories: 680
- Sugar: 5g
- Sodium: 620mg
- Fat: 42g
- Saturated Fat: 21g
- Unsaturated Fat: 17g
- Trans Fat: 1g
- Carbohydrates: 32g
- Fiber: 2g
- Protein: 38g
- Cholesterol: 145mg
Keywords: meatloaf, mac and cheese, comfort food

