If you’re craving something elegant yet comforting, Garlic Butter Shrimp Scampi Lasagna is your perfect dish. This twist on classic lasagna blends tender shrimp with rich garlic butter, creamy white sauce, and layers of perfectly cooked noodles. It’s a seafood lover’s dream tucked between cheesy, golden-baked layers.

This lasagna recipe brings the savory flavor of shrimp scampi into a satisfying casserole format. It’s perfect for dinner parties, date nights at home, or simply treating yourself to something extraordinary. The garlic butter sauce and herbs create layers of richness that make each bite irresistible.

Preparation Phase & Tools to Use

Before diving into cooking, it’s important to have the right tools on hand to make your Garlic Butter Shrimp Scampi Lasagna come together smoothly:

Large Skillet or Sauté Pan: For searing shrimp and creating the garlic butter scampi sauce. Even heat distribution is key here.
Large Pot: To boil the lasagna noodles evenly.
9×13 Baking Dish: This is the classic vessel for lasagna, allowing the layers to set well and bake evenly.

Mixing Bowls: For combining cheese mixtures and layering ingredients efficiently.
Whisk & Wooden Spoon: The whisk helps blend sauces without lumps, while the spoon is perfect for stirring without damaging your nonstick surfaces.
Aluminum Foil: Covering the lasagna during the first half of baking keeps it moist before the cheese topping browns.

With these tools at the ready, you’re all set to build a lasagna that delivers bold flavor and creamy texture in every bite.

Ingredients for the Garlic Butter Shrimp Scampi Lasagna

Each ingredient in this recipe plays a specific role to create the balance of creamy, garlicky, and seafood-rich flavor:

Lasagna noodles: The foundation of the dish. These wide, flat noodles hold everything together and provide texture.

Raw shrimp (peeled & deveined): The star ingredient. Their sweetness and delicate texture make the lasagna rich and flavorful.
Butter: Essential for the scampi base. Adds depth and silkiness to the garlic sauce.
Garlic (minced): Sharp, savory, and aromatic—the key note of the entire dish.

Heavy cream: For the white sauce. It gives the lasagna a velvety richness.
Parmesan cheese (freshly grated): Adds umami and thickens the sauce.
Ricotta cheese: For creamy layering and mild richness.

Mozzarella cheese (shredded): Melts beautifully and gives that cheesy, bubbly top layer.
Fresh parsley: Brightens the flavor and enhances presentation.
Salt and pepper: Essential seasoning to balance all the flavors.

How To Make the Garlic Butter Shrimp Scampi Lasagna

Step 1: Cook the Lasagna Noodles

Boil the noodles in salted water until al dente. Drain and lay them flat on parchment paper or drizzle with olive oil to prevent sticking.

Step 2: Prepare the Garlic Butter Shrimp

In a skillet, melt butter over medium heat. Add minced garlic and cook for 1 minute. Toss in shrimp, season with salt and pepper, and cook just until pink. Remove from heat and set aside.

Step 3: Make the Creamy Scampi Sauce

In the same skillet, add a little more butter if needed and pour in the heavy cream. Whisk continuously, then add Parmesan cheese. Simmer until it thickens slightly. Adjust seasoning to taste.

Step 4: Assemble the Layers

Spread a bit of sauce on the bottom of your baking dish. Add a layer of noodles, a scoop of ricotta, a sprinkle of shrimp, drizzle of sauce, and a handful of mozzarella. Repeat until all components are used, finishing with a generous top layer of mozzarella and parsley.

Step 5: Bake to Perfection

Cover with foil and bake at 375°F (190°C) for 25 minutes. Remove foil and bake an additional 10-15 minutes until the top is golden and bubbly. Let it rest for 10 minutes before slicing.

How to Serve and Store Garlic Butter Shrimp Scampi Lasagna

Serve this decadent lasagna with a simple green salad and garlic bread to round out the meal. A light white wine like Sauvignon Blanc or Pinot Grigio pairs beautifully with the buttery richness of the dish.

For storing, allow leftovers to cool completely. Refrigerate in an airtight container for up to 3 days. You can also freeze portions by wrapping them tightly in plastic wrap and foil—they’ll keep for up to 2 months. Reheat in the oven or microwave until warmed through, adding a splash of cream if needed to bring back moisture.

Frequently Asked Questions

How do I keep the lasagna from being too watery?

Be sure to drain the shrimp well and avoid overloading the layers with sauce. Letting the lasagna rest before slicing also helps it firm up.

Can I use pre-cooked shrimp?

Yes, but add them at the end of the sauce stage to avoid overcooking. Raw shrimp develop better flavor when cooked directly in the garlic butter.

Is there a substitute for ricotta cheese?

You can use cottage cheese or a mascarpone blend, though ricotta delivers the best traditional texture.

Can this be made ahead of time?

Absolutely. Assemble the lasagna a day ahead and refrigerate it unbaked. When ready to serve, bake as instructed, adding an extra 5-10 minutes if it’s straight from the fridge.

What’s the best way to reheat leftovers?

The oven works best for even heating and preserving texture. Microwave is quicker but may slightly affect consistency. Cover with foil to prevent drying out.

Want More Seafood Dinner Ideas?

If you love this Garlic Butter Shrimp Scampi Lasagna, here are a few other seafood-rich comfort meals you might enjoy from my blog:

Seafood Stuffed Shells for a cheesy, oven-baked seafood classic.
Creamy Garlic Butter Lobster Tails for an indulgent date-night meal.

Baked Crab Legs in Butter Sauce for a simple yet luxurious dinner.
Creamy Jamaican Shrimp Rasta Pasta with bold island spices.
Honey Garlic Shrimp Sausage Broccoli if you’re craving quick, savory skillet meals.

Save This Recipe for Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time: Follow me here for daily dishes.

And let me know in the comments how yours turned out. Did you add a twist with Cajun spice? Or layer in some spinach for extra greens?

I always love hearing your ideas and tweaks—don’t be shy to ask questions or share your version of this creamy, garlicky delight!

Garlic Butter Shrimp Scampi Lasagna

Author: Olivia McKenney
Total Time: 1 hour 10 minutes
Yield: 8 servings

Print Recipe

Description

Garlic Butter Shrimp Scampi Lasagna is a creamy, rich seafood twist on the Italian classic. Featuring layers of tender shrimp sautéed in garlic butter, a velvety white sauce, ricotta, mozzarella, and Parmesan, it’s baked to golden perfection. Perfect for cozy dinners, special occasions, or whenever you’re craving an indulgent comfort meal.

Instructions

1. Cook lasagna noodles in salted water until al dente. Drain and lay flat on parchment paper or drizzle with olive oil to prevent sticking.

2. In a large skillet, melt 4 tablespoons of butter over medium heat. Add garlic and cook for 1 minute until fragrant. Add shrimp, season with salt and pepper, and cook until pink. Set aside.

3. In the same skillet, add 2 tablespoons butter and pour in heavy cream. Whisk continuously and add Parmesan cheese. Simmer until slightly thickened. Season as needed.

4. Preheat oven to 375°F (190°C). Spread a layer of sauce on the bottom of a 9×13 baking dish.

5. Add a layer of noodles, spread some ricotta, add shrimp, drizzle with sauce, and sprinkle mozzarella. Repeat layers until ingredients are used, finishing with mozzarella and parsley on top.

6. Cover with foil and bake for 25 minutes. Remove foil and bake for 10–15 minutes more until bubbly and golden.

7. Let rest for 10 minutes before slicing and serving.