If comfort food had a crown, this Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce would wear it proudly. Tender spaghetti is twirled through a velvety, garlicky cheese sauce infused with Cajun spices, then topped with juicy slices of blackened chicken. The aroma alone is enough to draw everyone into the kitchen, but that first bite—rich, creamy, with just the right kick—will make them stay for seconds.

This dish blends the soul-warming familiarity of pasta night with a bold Cajun twist. The creamy garlic mozzarella sauce clings to every strand of spaghetti, while the chicken brings smoky, savory depth. Perfect for a weeknight indulgence or a dinner party showstopper, it’s a recipe that delivers comfort and flair in every forkful.

Preparation Phase & Tools to Use

To make the magic happen, you’ll need a few essential tools that ensure everything comes together smoothly:

Large pot for boiling pasta – Gives the spaghetti room to cook evenly and prevents clumping.
Heavy-bottomed skillet or cast iron pan – Ideal for searing chicken to perfection and locking in juices while achieving that Cajun crust.
Wooden spoon or silicone spatula – Gentle on your pans and perfect for stirring the sauce without scratching.

Tongs – Makes flipping the chicken easy and keeps your hands safe from splattering oil.
Fine grater or microplane – For fresh garlic and finely grated mozzarella that melts seamlessly into the sauce.

Having the right tools means you can focus on the fun part: creating a creamy, flavor-packed pasta that looks as irresistible as it tastes.

Ingredients for the Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Spaghetti – The classic pasta base that soaks up the creamy sauce.
Chicken breasts – Lean protein that carries the Cajun seasoning beautifully.
Cajun seasoning – Brings the signature smoky, spicy flavor to the dish.

Olive oil – Helps sear the chicken and adds a subtle richness.
Garlic cloves – Freshly minced for a fragrant, savory depth.
Heavy cream – Creates the luscious, velvety sauce.

Mozzarella cheese – Melts into the sauce for gooey, cheesy indulgence.
Butter – Adds richness and helps build the sauce’s base.
Fresh parsley – Brightens the dish and adds a pop of color.

Salt & pepper – For balancing and enhancing all the flavors.

How To Make the Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Step 1: Season and Sear the Chicken

Pat chicken breasts dry, then coat generously with Cajun seasoning, salt, and pepper. Heat olive oil in a heavy skillet over medium-high heat and sear chicken for 4-5 minutes per side, until golden and cooked through. Remove from skillet and let rest.

Step 2: Boil the Pasta

While the chicken cooks, bring a large pot of salted water to a boil. Add spaghetti and cook until al dente. Drain and set aside, reserving about 1/2 cup of pasta water.

Step 3: Build the Garlic Mozzarella Sauce

In the same skillet used for the chicken, melt butter over medium heat. Add minced garlic and cook until fragrant, about 30 seconds. Pour in heavy cream and stir, scraping up any browned bits from the bottom of the pan.

Step 4: Add the Cheese and Seasoning

Reduce heat to low and stir in mozzarella cheese until smooth and creamy. Adjust seasoning with salt, pepper, and extra Cajun spice if desired.

Step 5: Combine Pasta and Sauce

Add cooked spaghetti to the skillet, tossing gently to coat. If the sauce is too thick, add a splash of reserved pasta water to loosen it.

Step 6: Slice and Serve

Slice the rested chicken into strips and arrange over the pasta. Sprinkle with fresh parsley before serving.

Serving and Storing Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Serve this pasta hot, straight from the skillet, for the ultimate creamy experience. It pairs beautifully with a crisp green salad and warm garlic bread to soak up every drop of sauce. A chilled glass of white wine or iced tea makes a refreshing contrast to the rich, spicy flavors.

If you have leftovers, let them cool completely before transferring to an airtight container. Refrigerate for up to 3 days. Reheat gently in a skillet over low heat, adding a splash of cream or milk to restore the sauce’s silky texture. Freezing is not recommended, as the cream sauce may separate upon thawing.

Frequently Asked Questions

Can I use a different pasta shape?

Yes! Fettuccine, linguine, or even penne will work well, though spaghetti gives the best twirl with the creamy sauce.

How can I make it less spicy?

Simply reduce the Cajun seasoning or choose a mild blend. You can also balance the heat with a little extra cream.

Can I use pre-cooked chicken?

Yes, but searing fresh chicken in Cajun seasoning gives the dish a richer flavor and juicier texture.

What if my sauce is too thick?

Add a splash of reserved pasta water or cream while stirring over low heat until it reaches your desired consistency.

Can I make it ahead?

You can cook the chicken and sauce in advance, then reheat and toss with freshly cooked pasta right before serving.

Is there a dairy-free option?

Swap the heavy cream for coconut cream and use dairy-free mozzarella for a creamy, lactose-free version.

Want More Pasta Ideas?

If you love this Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce, you’ll probably enjoy these other favorites from my collection:

One-Pan Creamy Cajun Honey Garlic Steak Pasta for a rich, bold twist with tender steak.
Cheesy Garlic Chicken and Broccoli Pasta if you want extra veggies in your creamy pasta.

Creamy Garlic Butter Chicken Rotini in Parmesan Sauce for another cheesy, indulgent dinner.
Sweet Spicy Garlic Honey BBQ Chicken Pasta if you’re in the mood for a sweet-heat balance.
Creamy Jamaican Shrimp Rasta Pasta Recipe when you’re craving tropical flair.

For even more recipes to inspire your next meal, check out my Pinterest Life With Olivia board where I share daily kitchen creations.

Save This Recipe for Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And when you try it, tell me how it turned out! Did you kick up the Cajun heat or keep it mild? Add extra cheese or maybe even swap in shrimp? I love hearing how you make these recipes your own. Let’s keep sharing tips and cooking smarter together.

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Author: Olivia McKenney
Total Time: 30 minutes
Yield: 4 servings

Print Recipe

Description

A creamy, flavorful pasta dish with tender Cajun-seasoned chicken over spaghetti, coated in a luscious garlic mozzarella sauce. Perfect for a cozy dinner with just the right balance of heat and comfort.